Foods High in Polyphenols: The Richest Sources

Olive oil, brewed coffee, mixed berries, and cocoa powder with star anise on a cloth-covered table.

Key Takeaways

  • Foods high in polyphenols include berries, herbs and spices, nuts and seeds, and dark vegetables. Coffee, tea, and extra-virgin olive oil are meaningful daily sources.
  • Polyphenols are plant compounds that act as antioxidants and help your cells turn on their own defenses.
  • Cloves, dried herbs, dark berries, and cocoa are the highest polyphenol foods by weight. Covering a range of foods with polyphenols each week is what shapes your actual intake.
  • Your gut bacteria turn polyphenols into forms your body can use. These foods and your gut help each other.
  • With olive oil, look for extra-virgin, a recent harvest date, and a peppery finish. Those three signs point to a higher-polyphenol bottle.

You keep running into the word. It shows up on tea labels and olive oil bottles, in podcasts about healthy aging, and in nearly every article about eating well after 40. Polyphenols. Somehow the word arrives without ever explaining what these compounds are or where to find them.

The foods high in polyphenols worth knowing are dried herbs and spices, cocoa, dark berries, nuts and seeds, coffee, tea, and extra-virgin olive oil. What follows is what these compounds are, which of them carry the most, and how to work more foods rich in polyphenols into an ordinary week.

What Are Polyphenols?

Polyphenols are a large family of natural compounds found in plants, and they are one of the main reasons a varied, plant-rich diet supports healthy aging. More than 8,000 polyphenols have been identified in plants so far, though the number that shows up in measurable amounts in the human diet is far smaller. They fall into four broad classes: flavonoids (the pigments in berries and onions), phenolic acids (abundant in coffee), stilbenes (such as resveratrol in grapes), and lignans (concentrated in flaxseed).

Plants make polyphenols for their own protection, as a defense against ultraviolet light, pests, and other stresses the plant turns to its advantage. That is why the compounds concentrate in the parts most exposed to the outside world: skins, seeds, and the deeply colored flesh of fruits and vegetables. The bitter edge of dark chocolate and the drying grip of strong tea both come from polyphenols doing their original job in the plant, and so does the near-black color of an elderberry.

Polyphenols are not vitamins or minerals, and the body does not depend on them the way it depends on essential nutrients. There is no official recommended daily amount for them, which is part of why the practical question is simply which foods high in polyphenols show up on your plate.

What Do Polyphenols Do for the Body?

The clearest benefit of polyphenols is antioxidant support, and it works in two distinct ways. Polyphenols neutralize free radicals directly, the reactive molecules that build up as a normal byproduct of living and that the body has to keep in balance. They do this in both the watery inside of cells and the fatty membranes around them, which is why a mix of polyphenols reaches places a single compound cannot.

The second action is more interesting, and it is where the science has moved in recent years. Beyond mopping up free radicals themselves, some polyphenols prompt the cell to raise its own antioxidant defenses. Curcumin and resveratrol are both described as activators of Nrf2, a transcription factor that switches on a battery of the cell’s own protective genes. The same review is candid that these polyphenols are weaker Nrf2 activators than sulforaphane, the compound from broccoli, so the effect is real but modest.

Still, it is why the effect of polyphenols is broader than any test-tube antioxidant score would suggest. The compound does some of the work directly and prompts the cell to do the rest. That second layer matters more with age, because oxidative stress rises as the body’s own defenses slow, and it tends to travel alongside the low-grade inflammation that comes with aging.

At the level of whole diets, the pattern is consistent. People eating a polyphenol-rich diet tend to show better cardiovascular and healthy-aging markers, an association reported in the PREDIMED cohort described below. The evidence is strongest for dietary patterns rather than for any single polyphenol taken on its own, so these findings describe an association between the pattern and the markers, and nothing stronger.

Evidence Anchor icon.

The science: Diets high in polyphenols are associated with a lower risk of cardiovascular events in older adults, which is one of the reasons polyphenol-rich eating is studied so heavily in the context of healthy aging.

The evidence: In an observational analysis within the PREDIMED trial, 7,172 older adults at high cardiovascular risk were followed for an average of 4.3 years, during which 273 cardiovascular events occurred. Participants in the highest fifth of habitual total polyphenol intake had a lower incidence of major cardiovascular events than those in the lowest fifth. The authors note that clinical trials are still needed to confirm the effect.

What the studies used: This is observational evidence on what people already ate, not a dosing trial, so there is no trial dose to compare against any ResilienZ-12™ amount.

Foods High in Polyphenols: The Richest Sources

Cloves, dried mint, a spoon of cocoa powder, and star anise on a dark slate surface.

The highest polyphenol foods by weight are dried spices, cocoa, and dark-pigmented berries, though the foods that contribute most to a real diet are often the ones eaten in larger amounts, such as coffee and berries. That distinction matters. A gram of cloves is denser in polyphenols than almost anything else on earth, but nobody eats cloves by the handful. The foods with most polyphenols per gram and the foods that deliver the most polyphenols across a day are two overlapping but different lists.

If you want the foods with most polyphenols measured strictly per gram, the spice rack wins. Content also varies widely within any single food. Variety, ripeness, growing conditions, processing, and cooking all shift the numbers, and Phenol-Explorer added a whole dataset on processing losses for exactly that reason. Read the values below as solid benchmarks that still move from one sample to the next.

Total polyphenol content of selected foods Cloves 15,188; dried peppermint 11,960; star anise 5,460; cocoa powder 3,448; black chokeberry 1,756; dark chocolate 1,664; flaxseed meal 1,528; black elderberry 1,359; highbush blueberry 560; blackberry 260; filter coffee 214 (mg per 100 g, or per 100 mL for coffee). Source: Phenol-Explorer, Pérez-Jiménez et al. 2010. Cloves (dried) 15,188 mg Dried peppermint 11,960 mg Star anise 5,460 mg Cocoa powder 3,448 mg Black chokeberry 1,756 mg Dark chocolate 1,664 mg Flaxseed (meal) 1,528 mg Black elderberry 1,359 mg Highbush blueberry 560 mg Blackberry 260 mg Coffee, filter 214 mg Source: Phenol-Explorer (Pérez-Jiménez et al., 2010). Coffee value per 100 mL; all others per 100 g.
Figure 1. Total polyphenols by weight. Spices and cocoa dominate per gram; everyday foods like coffee and berries contribute more across a full day because portions are larger. These are the total-content figures from the source table. The same paper also reports lower values for several of these foods using a stricter measurement method. Treat these numbers as upper-end benchmarks, not precise doses.

The foods rich in polyphenols cluster in four categories.

Herbs, Spices, and Cocoa: The Highest Polyphenol Foods by Weight

Gram for gram, dried herbs and spices sit at the very top, and cocoa is close behind. Cloves, dried peppermint, star anise, and oregano carry some of the highest polyphenol concentrations measured in any food, and cocoa flavanols are among the most studied polyphenols for cardiovascular research. The catch is portion size. A teaspoon of oregano or a square of dark chocolate adds real polyphenols, but the amounts are small, so the highest polyphenol foods by density work best as a steady seasoning habit rather than a main source.

Turmeric belongs in this group too, as the source of curcumin, one of the most researched dietary polyphenols. Curcumin is also a useful illustration of a problem that runs through this whole topic: absorption. Curcumin is famously hard for the body to take up from food or turmeric on its own, which is why formulators pay so much attention to delivery form. ResilienZ-12™ uses Meriva® Curcumin Phytosome®, a form developed by Indena® in which curcumin is bound to a lipid to improve how much reaches circulation.

Berries, Fruits, and Vegetables: Everyday Foods Rich in Polyphenols

Fresh fruit and vegetables on a cream cloth: blackberries, blueberries, red onions, plums, figs, kale, spinach, and an artichoke.

Dark berries are the most practical of the everyday foods rich in polyphenols, because the portions are generous and the density is high. Blackberries, blueberries, black currants, and elderberries owe their deep color to anthocyanins, the pigments behind deep red and purple color, and cherries and plums add more of the same. Among vegetables, artichokes, red onion, and spinach are reliable contributors, with quercetin especially concentrated in onions.

Blueberries are worth a note of their own, because not all of them are equal. In the same source table, lowbush blueberries (the small wild kind, often sold frozen) come in at 836 mg per 100 g, while the larger cultivated highbush berries come in at 560. Both are good. The wild ones are simply more concentrated, which is a reasonable tiebreaker in the freezer aisle.

This is the chemistry underneath the familiar advice to eat the rainbow, and it is why foods rich in polyphenols are easy to spot on sight. The pigments that make produce red, purple, and blue are frequently the polyphenols themselves, so a plate built around color tends to be a plate built around polyphenol-rich foods without any extra effort. It also overlaps heavily with the broader list of antioxidant-rich foods worth keeping in weekly rotation.

Nuts, Seeds, and Legumes: Foods With Polyphenols and Fiber Together

Nuts and seeds are foods with polyphenols and fiber in the same bite, along with healthy fats, which is a useful pairing. Chestnuts, hazelnuts, and pecans carry meaningful amounts, and flaxseed is the richest common dietary source of lignans, a polyphenol class linked to the gut. Black beans and other dark legumes are further foods with polyphenols worth keeping in the pantry.

The fiber in these foods does real work. Fiber-bound polyphenols travel to the lower gut still attached to the plant matrix, where gut bacteria go to work on them, which is the bridge to the next section.

Coffee, Tea, and Extra-Virgin Olive Oil

Beverages are the biggest real-world contributors to daily intake for many people, and coffee is the largest of the drinkable foods with polyphenols. Across 36,037 adults in 10 European countries, coffee, tea, and fruit were the most important food sources of total polyphenols. Green and black tea contribute catechins, including EGCG, along with the theaflavins that form in black tea.

Extra-virgin olive oil rounds out the group, carrying hydroxytyrosol and oleuropein, the compounds behind its faint bitterness. Extra-virgin matters here because refining strips much of the polyphenol content. As a daily cooking and dressing fat, good olive oil is one of the easier foods high in polyphenols to use consistently.

Which Olive Oil Has the Most Polyphenols?

The olive oil with the most polyphenols is an extra-virgin oil from a recent harvest, sold in dark glass or tin, with a peppery finish. Where a producer prints a measured polyphenol number, that figure settles the question outright. Content varies enough between bottles that this is worth a minute in the aisle, and it is one of the few corners of the polyphenol world where a hard number exists.

European regulators authorized a health claim for olive oil polyphenols, and the condition attached to it is specific. The oil must carry at least 5 mg of hydroxytyrosol and related compounds per 20 g of olive oil. The stated benefit is tied to eating 20 g a day, about a tablespoon and a half. That threshold is the closest thing the category has to a benchmark, and producers who test their oil often print the figure on the label or the harvest sheet.

What Are the Most Potent Polyphenols in Olive Oil?

The most potent polyphenols in olive oil are hydroxytyrosol, oleocanthal, and oleacein. Olive oil carries a small, distinctive set of these compounds, unlike the broad mix found in berries or spices. Hydroxytyrosol is the one the European threshold is written around, and it travels with a close relative called tyrosol. Oleuropein is the parent compound in the fruit itself, and as the olives ripen and the oil is pressed it breaks down into oleocanthal and oleacein, the two that give a fresh oil its character.

Oleocanthal is also the reason a good oil bites. The compound was named for the stinging sensation it produces at the back of the throat, and the laboratory work that identified it reported that the sting tracks a shared ability to block the same inflammation enzymes ibuprofen acts on. That is a finding about a molecule measured in a laboratory, not a suggestion that olive oil works as a painkiller. What it does give you is a reliable shortcut. If the oil catches at the back of your throat, the polyphenols are still there.

How to Check the Polyphenols in Olive Oil

Where no number is printed, four cues narrow the field.

  1. Grade. Extra-virgin is the grade that retains the most. Refining strips most of it, which is why "light" and "pure" olive oils are not contenders.
  2. Harvest date. A printed harvest date beats a best-before date, and recent beats distant. Polyphenols fall steadily in the bottle.
  3. Packaging. Dark glass or tin over clear glass, because light accelerates the same decline.
  4. Taste. Bitter on the tongue, peppery at the back of the throat.

The harvest-date advice has real numbers behind it. Tracking two single-variety oils month by month for a year, researchers measured total phenol declines of 15% and 32% over 12 months of storage, with oleocanthal falling 19% in one oil and 43% in the other. For perspective, both oils still met the European threshold at the end of the year, so an older bottle is not a wasted one. Fresher is simply better, and the gap widens with the oils that started highest.

Polyphenol-Rich Foods for Gut Health

Halved figs, blackberries, blueberries, oats, and flax seeds on a beige surface.

Polyphenol-rich foods and gut health support each other in a two-way exchange, which is a large part of why the two topics keep appearing together. Most dietary polyphenols are poorly absorbed in the upper gut and travel largely intact to the colon, where resident bacteria convert them into smaller compounds the body can absorb and use. Without that microbial step, much of a polyphenol’s activity would never reach circulation.

A major review of polyphenol bioavailability makes the point bluntly: after you eat them, polyphenols do not reach the blood as the original compounds. The body converts them first, and those converted forms circulate at extremely low levels. The laboratory studies behind many of the exciting headlines used the original compounds at concentrations thousands of times higher. That gap is a good reason to be skeptical of any single dramatic claim, and a good reason to think in terms of dietary patterns instead.

The exchange runs in the other direction as well. Polyphenols and their fiber act like prebiotics, feeding beneficial gut bacteria and shaping a favorable microbial balance. So polyphenol-rich foods feed the microbes, and the microbes make those polyphenols usable.

The partnership also helps explain why people respond differently to the same foods. The bacteria needed to convert certain polyphenols into their active forms are present in some guts and not others, so two people eating the identical berry can end up with different compounds in their blood. It is one more reason whole foods, fiber included, tend to serve you better than an isolated compound.

How Much Polyphenol Intake Per Day?

There is no official target for how much polyphenols per day anyone should get. Population studies do give a rough sense of scale. In the EPIC study, which measured intake across 10 European countries, average daily intake ranged from 584 mg among women in Greece to 1,786 mg among men in Aarhus, Denmark. That is a threefold spread between ordinary populations eating ordinary food, which tells you more about how loose the target is than any single number would.

The practical translation is simpler than the milligram question suggests. For how much polyphenols per day, the useful target is several servings across different categories. A day that hits the mark might look like this:

  1. Coffee or tea with breakfast, plus a handful of dark berries.
  2. A lunch that includes leafy greens or another deeply colored vegetable, dressed with extra-virgin olive oil.
  3. Nuts or seeds as a snack, ideally with the skins on.
  4. An evening meal seasoned generously with herbs and spices, with a square of dark chocolate if you want one.

Color, variety, and a little consistency are what that day asks for.

How to Eat More Foods High in Polyphenols

A green salad on a plate, with black coffee, mixed berries, fresh herbs, nuts, and a square of dark chocolate.

The most reliable way to eat more foods high in polyphenols is to build meals around color and category. A polyphenol-rich diet works as a weekly pattern you repeat. A varied plate covers more polyphenol classes, and because the food matrix (the whole food a compound arrives in) and its fiber shape how much your body absorbs, whole foods tend to outperform isolated extracts in everyday eating.

A polyphenol-rich diet is built from a few durable habits.

  • Lean on coffee, tea, and extra-virgin olive oil, since they show up daily anyway.
  • Keep herbs and spices generous.
  • Reach for whole and minimally processed versions, since processing tends to strip polyphenols.
  • Favor deeply colored produce whenever there is a choice, because that is where foods high in polyphenols concentrate.

These are small moves that compound over years, and they are easier to keep than any short-term overhaul.

The strongest evidence for this approach comes from studies of whole eating patterns. The Mediterranean diet, rich in olive oil, vegetables, nuts, and other polyphenol sources, was associated with a lower rate of major cardiovascular events in the PREDIMED trial.

A varied, colorful plate you can repeat every week is the whole strategy.

Polyphenol Supplements: Where They Fit

A bottle of ResilienZ-12™ Advanced Antioxidants & Phytochemical Complex beside a coffee mug, blackberries, a notebook, and a sprig of rosemary.

Diet is the foundation, and a plate built from foods rich in polyphenols is where the benefits show up most reliably. Even so, two honest gaps remain. Some polyphenols are poorly absorbed from food, and few people eat as broad a range of plants as they would like every week. That narrow space is where a well-formulated supplement can support a polyphenol-rich diet rather than stand in for it.

The category attracts a lot of loose marketing, so the limits are worth stating plainly. A polyphenol supplement does not replicate a plant-rich diet. It carries a handful of isolated compounds, not the hundreds that arrive across a varied week, and it arrives without the fiber and food matrix that shape how those compounds behave in the gut. Broad-spectrum "polyphenol blends" that list a dozen botanical extracts without stating a dose for any of them are the clearest sign to keep walking, which is the same reasoning behind avoiding proprietary blends generally.

Where polyphenols in supplements earn their place is narrower and more specific: a specific compound, at the dose its research used, in a form the body can absorb. Curcumin is the clearest example of that absorption gap. It is poorly taken up from turmeric on its own, and delivery form changes that substantially, which is a question about the ingredient itself rather than a health claim.

Four of the polyphenol ingredients in ResilienZ-12™ come from these same food sources, and they sit across three of the four pillars in the Four-Pillar Framework, covering the direct antioxidant defense the earlier sections described as well as the signaling and cleanup roles that work with it:

  • Signal pillar: Trans-resveratrol (a stilbene related to the polyphenols in grapes)
  • Shield pillar: Meriva® Curcumin Phytosome® (a lipid-bound curcumin from Indena®)
  • Cleanup pillar: Quercetin (the flavonol also found in onions and apples)
  • Cleanup pillar: Decaffeinated green tea extract (a source of EGCG)

Quercetin and EGCG carry the Cleanup role, tied to autophagy, the cellular renewal process the body uses to recycle worn-out components. These ingredients are here to support a good diet where food falls short. Where a food-derived polyphenol is hard to absorb, or hard to get enough of across a week, a bioavailable form, one the body can absorb well, can back up what a good diet already provides.

Evidence Anchor icon.

The science: Curcumin, the primary polyphenol in turmeric, is poorly absorbed in its plain form. Binding it to a lipid (a phytosome) improves how much reaches the bloodstream. This is an ingredient-form question, not a claim about a health outcome.

The evidence: In absorption research, total curcuminoid absorption was about 29 times higher for the phytosome form than for the unformulated curcuminoid mixture. The same paper notes that only the body’s converted forms were detectable, at plasma concentrations still below the levels most of curcumin’s anti-inflammatory targets would require. Some of this research was funded by the ingredient manufacturer. Absorption studies describe how much of a compound reaches circulation, not what it does once there.

What the studies used: The absorption study compared the phytosome form against an unformulated curcuminoid mixture at two dose levels, 209 mg and 376 mg of curcuminoids. ResilienZ-12™ provides 500 mg of Meriva® Curcumin Phytosome®, about 100 mg of curcuminoids, chosen as a foundational daily amount rather than to match a short-term study dose. That is below the amounts used here, so read the finding as a fact about the delivery form rather than a claim about what this amount does.

Studies cited above describe dietary patterns and individual ingredients, not the ResilienZ-12™ formula. Ingredient and dose selection in ResilienZ-12™ is informed by this research, not equivalent to it.

The Bottom Line: Building a Polyphenol-Rich Diet

A polyphenol-rich diet is within reach for most people, and it is the foundation worth building first. Cover the categories across a week: berries and dark produce, herbs and spices, nuts and seeds, coffee and tea, and a good extra-virgin olive oil. That spread is what a polyphenol-rich diet looks like in practice.

Eat them with their fiber and keep the habit consistent. Your gut handles the rest. Where diet runs thin or a valuable polyphenol is hard to absorb from food, the food-derived polyphenol ingredients in ResilienZ-12™ can support what a varied plate already builds.

Frequently Asked Questions

What foods are high in polyphenols?

Foods high in polyphenols include herbs and spices, dark berries, cocoa, nuts and seeds, coffee, tea, and extra-virgin olive oil. Cloves and dried herbs are the highest polyphenol foods by weight, while coffee and berries often contribute the most in a typical diet because portions are larger.

What foods have the most polyphenols?

The highest polyphenol foods by weight are dried spices and cocoa, led by cloves, dried peppermint, and star anise, followed by cocoa powder and dark berries such as aronia and elderberry. Per-gram density is highest in spices, though real-world intake leans on larger-portion foods.

What are examples of polyphenols?

Common examples include quercetin in onions and apples, catechins such as EGCG in green tea, anthocyanins in dark berries, chlorogenic acids in coffee, curcumin in turmeric, resveratrol in grapes, hydroxytyrosol and oleuropein in olive oil, and lignans in flaxseed. They belong to four broad classes: flavonoids, phenolic acids, stilbenes, and lignans.

Are polyphenols antioxidants?

Yes, and they do more than that. Polyphenols act as direct antioxidants, neutralizing free radicals in both watery and fatty parts of the cell. Some also prompt cells to raise their own antioxidant defenses through the Nrf2 pathway, which is why their effect is broader than a simple antioxidant score would suggest.

Does coffee have polyphenols?

Yes. Coffee is one of the largest polyphenol contributors in many European and North American diets, thanks to its chlorogenic acids. In the EPIC study of more than 36,000 adults, coffee, tea, and fruit were the top three food sources of total polyphenols.

Does green tea have polyphenols?

Yes. Green tea’s main polyphenols are catechins, especially EGCG. Black and oolong teas also contribute polyphenols through theaflavins, which form when tea leaves oxidize. All true teas are meaningful polyphenol sources, and they add to daily totals alongside coffee.

How can you check the polyphenols in olive oil?

The most direct check is the label. European rules allow a polyphenol health claim only for oils carrying at least 5 mg of hydroxytyrosol and related compounds per 20 g, so producers who test often print that figure. Where no number appears, look for extra-virgin grade, a recent harvest date, dark glass, and a peppery finish.

Does decaf coffee have polyphenols?

Yes, and nearly as many as regular coffee. Taking the caffeine out does not take out the chlorogenic acids, which carry most of coffee’s polyphenol content. One analysis of arabica coffees found only 3 to 9 percent less chlorogenic acid in roasted decaf than in regular coffee. Decaf still counts toward your daily total.

What are the most potent polyphenols in olive oil?

Hydroxytyrosol and its related compounds are the ones European regulators wrote the olive oil health claim around. Oleuropein is the parent compound in the fruit, and it converts during pressing into oleocanthal and oleacein. Oleocanthal is what produces the peppery sting at the back of the throat in a fresh oil.

Do polyphenol supplements work?

Polyphenol supplements can supply specific compounds in bioavailable forms, but they do not replicate a plant-rich diet, since they lack the fiber and food matrix that shape how polyphenols behave in the gut. Judge them as you would any supplement: a named compound, a dose that matches the research, and a form the body can absorb. Blends that list many extracts without stating individual doses are the ones to skip.

How much polyphenols per day should you have?

There is no official daily requirement for polyphenols. European intake surveys put ordinary daily consumption somewhere between roughly 600 and 1,800 mg depending on the country, and separate research in older adults links higher habitual intake with fewer cardiovascular events. The practical target is variety across polyphenol-rich foods rather than a specific number.

FDA Disclaimer

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

This article draws on 15 peer-reviewed sources, all linked in the references below.

References

Beauchamp, G. K., Keast, R. S. J., Morel, D., Lin, J., Pika, J., Han, Q., Lee, C.-H., Smith, A. B., & Breslin, P. A. S. (2005). Phytochemistry: Ibuprofen-like activity in extra-virgin olive oil. Nature, 437(7055), 45–46.

Cardona, F., Andrés-Lacueva, C., Tulipani, S., Tinahones, F. J., & Queipo-Ortuño, M. I. (2013). Benefits of polyphenols on gut microbiota and implications in human health. Journal of Nutritional Biochemistry, 24(8), 1415–1422.

Cory, H., Passarelli, S., Szeto, J., Tamez, M., & Mattei, J. (2018). The role of polyphenols in human health and food systems: A mini-review. Frontiers in Nutrition, 5, 87.

Cuomo, J., Appendino, G., Dern, A. S., Schneider, E., McKinnon, T. P., Brown, M. J., Togni, S., & Dixon, B. M. (2011). Comparative absorption of a standardized curcuminoid mixture and its lecithin formulation. Journal of Natural Products, 74(4), 664–669.

Del Rio, D., Rodriguez-Mateos, A., Spencer, J. P. E., Tognolini, M., Borges, G., & Crozier, A. (2013). Dietary (poly)phenolics in human health: Structures, bioavailability, and evidence of protective effects against chronic diseases. Antioxidants & Redox Signaling, 18(14), 1818–1892.

Estruch, R., Ros, E., Salas-Salvadó, J., Covas, M.-I., Corella, D., Arós, F., … Martínez-González, M. A. (2018). Primary prevention of cardiovascular disease with a Mediterranean diet supplemented with extra-virgin olive oil or nuts. New England Journal of Medicine, 378(25), e34.

European Commission. (2012). Commission Regulation (EU) No 432/2012 establishing a list of permitted health claims made on foods. Official Journal of the European Union, L 136, 1–40.

Farah, A., de Paulis, T., Moreira, D. P., Trugo, L. C., & Martin, P. R. (2006). Chlorogenic acids and lactones in regular and water-decaffeinated arabica coffees. Journal of Agricultural and Food Chemistry, 54(2), 374–381.

Frisina, M., Bonacci, S., Oliverio, M., Nardi, M., Vatrano, T. P., & Procopio, A. (2023). Storage effects on bioactive phenols in Calabrian monovarietal extra virgin olive oils based on the EFSA health claim. Foods, 12(20), 3799.

Houghton, C. A., Fassett, R. G., & Coombes, J. S. (2016). Sulforaphane and other nutrigenomic Nrf2 activators: Can the clinician’s expectation be matched by the reality? Oxidative Medicine and Cellular Longevity, 2016, 7857186.

Manach, C., Scalbert, A., Morand, C., Rémésy, C., & Jiménez, L. (2004). Polyphenols: Food sources and bioavailability. American Journal of Clinical Nutrition, 79(5), 727–747.

Ozdal, T., Sela, D. A., Xiao, J., Boyacioglu, D., Chen, F., & Capanoglu, E. (2016). The reciprocal interactions between polyphenols and gut microbiota and effects on bioaccessibility. Nutrients, 8(2), 78.

Pérez-Jiménez, J., Neveu, V., Vos, F., & Scalbert, A. (2010). Identification of the 100 richest dietary sources of polyphenols: An application of the Phenol-Explorer database. European Journal of Clinical Nutrition, 64(Suppl 3), S112–S120.

Rothwell, J. A., Pérez-Jiménez, J., Neveu, V., Medina-Remón, A., M’Hiri, N., García-Lobato, P., … Scalbert, A. (2013). Phenol-Explorer 3.0: A major update of the Phenol-Explorer database to incorporate data on the effects of food processing on polyphenol content. Database (Oxford), 2013, bat070.

Tresserra-Rimbau, A., et al. (2014). Inverse association between habitual polyphenol intake and incidence of cardiovascular events in the PREDIMED study. Nutrition, Metabolism & Cardiovascular Diseases, 24(6), 639–647.

Zamora-Ros, R., Knaze, V., Rothwell, J. A., Hémon, B., Moskal, A., Overvad, K., … Scalbert, A. (2016). Dietary polyphenol intake in Europe: The European Prospective Investigation into Cancer and Nutrition (EPIC) study. European Journal of Nutrition, 55(4), 1359–1375.

About the author: Seanna Marceaux, MS RDN, is ResilienZ Health’s Chief Science Officer and the dietitian who vetted the ResilienZ-12 formulation. A Texas-licensed registered dietitian nutritionist with nearly 20 years in public health and aging, she holds a master’s degree in Human Nutrition from Texas State University, where she teaches graduate nutrition courses, and she has published peer-reviewed research on nutrition and aging.

More about Seanna’s background, research, and role at ResilienZ Health

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